MP3 Frequency Sampling Rate
When MP3 files talk about frequency sampling rates of 44.1 kHz, they are not talking about how high or low the notes are. They are talking about the quality of the audio file.
For example, CDs typically cover an audio range of 20 Hz (very low sounds) to 20,000 Hz (very high sounds). But the sampling rate on a CD is 44.1 kHz. In essence that means that every second of sound that goes by, that sound is sampled 44,100 times. The mathematical properties of waves cause the maximum frequency recorded at this rate to be around 22,000 Hz. Since even the most accurate human ear only hears up to around 20,000 Hz, and most adults only hear up to 14,000 Hz or even lower, this is more than enough to cover a human ear's range.
If you cut the sampling rate down to 22.05 kHz to save file space, you would now only be reproducing sounds up to a maximum "high notes" area of around 11,000 Hz. Since even middle aged or older listeners can hear higher noises than that, it will cause music to sound flat or dull, losing all the high end aspects. It would be like listening to a great symphony but for some reason all the flutes and cymbals were played behind a thick mattress.
Therefore, while you might look at other adjustments to make to your audio file compression software, it's best to leave the frequency sampling rate at the default of 44.1 KHz. This truly gives your ears the best possible experience they can get.
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Music / MP3 Tips and Information